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Archivo del Autor: Belen De Leon

WWE SummerSlam 2019: Live updates, results and match ratings – CNET

Airing live right now on the WWE Network.
Source: CNET

A Quiet Place Part 2: Everything we know about the haunting sequel – CNET

Shh! John Krasinski is bringing moviegoers back to that horrific universe where noise = death.
Source: CNET

Lo que la falta de muertes inexplicables revela sobre la materia oscura

Una investigación defiende que los humanos podrían ser detectores de la materia oscura porque el impacto de una macropartícula sería similar al de una herida de bala. Que no se hayan descubierto muertes por ese motivo puede indicar que las partículas de esta misteriosa materia tienen un pequeño tamaño
Source: MIT

Ligar en tiempos de IA: esta 'app' de voz quiere buscar a la pareja ideal

Combinando el reconocimiento de voz y de emociones, la aplicación AIMM ayuda a que sus usuarios encuentren pareja en función de sus gustos y les proporciona asesoramiento para conocerse. Aunque los asistentes de voz podrían ser el futuro de las citas ‘online’, la herramienta aún tiene muchas limitaciones 
Source: MIT

3D-printing organs moves a few more steps closer to commercialization

New successes in printing vascular tissue from living cells point to the accelerating pace of development of 3D printing tissue — and eventually the ability to manufacture organs from small samples of cells.

Late last month Prellis Biologics announced a $8.7 million round of funding and some significant advancements that point the way forward for 3D printed organs while a company called Volumetric Bio based on research from a slew of different universities unveiled significant progress of its own earlier this year.

The new successes from Prellis have the company speeding up its timeline to commercialization including the sale of its vascular tissue structures to research institutions and looking ahead to providing vascularized skin grafts, insulin producing sells, and a vascular shunt made from the tissue of patients who need dialysis, according to an interview with Melanie Matheu, Prellis’ chief executive officer and co-founder.

The creation of a vascular shunt made from a patient’s own cells should increase the chances of the procedure working successfully, says Matheu. “[If] that shunt fails there aren’t many other options… and then people have ports put in their chest.” The proposed treatment from Prellis could increase quality of life and longevity of people who are waiting for a kidney,” according to Matheu. 

A few months earlier, a team of researchers led by bioengineers Jordan Miller of Rice University and Kelly Stevens of the University of Washington (UW) with collaborators from UW, Duke University, Rowan University and the design firm, Nervous System, revealed a model of an air sac that mimicked the function of human lungs. The model could deliver oxygen to surrounding blood vessels — creating vascular networks that mimic the body’s own passageways.

“One of the biggest road blocks to generating functional tissue replacements has been our inability to print the complex vasculature that can supply nutrients to densely populated tissues,� said Miller, assistant professor of bioengineering at Rice’s Brown School of Engineering, in a statement. “Further, our organs actually contain independent vascular networks — like the airways and blood vessels of the lung or the bile ducts and blood vessels in the liver. These interpenetrating networks are physically and biochemically entangled, and the architecture itself is intimately related to tissue function. Ours is the first bioprinting technology that addresses the challenge of multivascularization in a direct and comprehensive way.�

Miller has launched a startup to commercialize the research called Volumetric Bio. While the researchers have made their findings freely available through open source licenses, they’re hoping to commercialize the technology by selling their bioprinters and materials and reagents.

The technology that Miller and his team develops uses photoreactor chemicals that respond to light, so specific area of liquid solidify while others can be rinsed away. The problem is that most of these chemicals have been found to cause cancer, so Miller and his team found a replacement to the traditional photoreactors in an unlikely place — the supermarket aisle.

The researchers surmised that food dye might do the trick and Miller just went to the supermarket and picked up a dye that’s typically used in baking, according to a story in Scientific American.

“We were screaming with joy, because it was stunning how simple an idea it was; it immediately enabled us to make this dramatically more complex architecture,� Miller told the magazine.

Prellis has made significant strides of its own. Alongside the funding, the company announced the successful implantation of tumors in animal subjects that were made using the company’s vascular scaffolds. The target market for these tests is in drug discovery, where animal testing can prove the efficacy of new treatments before they’re used on people in drug trials.

The printed structures, a combination of living cells and hydrogels are designed to provide a sort of scaffolding that an animal’s own cells can build on. In the study, conducted at Stanford University, Prellis was able to fully graft a tumor onto an animal using just 200,000 cells — far fewer than what’s required for typical tumor studies, according to the company.

And, as the company noted, within eight weeks, researchers identified branched vasculature of up to 50 microns inside of the transplanted structures, which indicated the animal’s vasculature system had incorporated the scaffolding into its own circulatory system.

Prellis is actually pitching its pre-made vascular scaffolds to researchers for their work on 3D printed biologics. Scientists at pharmaceutical companies and universities including UC San Francisco, Johns Hopkins, UC Irvine, and Memorial Sloan Kettering, are developing tests with standardized tissue structures (something that’s important for drug trials).

The drug discovery applications alone are a multi-billion dollar market, says Matheu, but the company is focused on its goal of fully transplantable 3D printed organs, starting with kidneys. The company is going to do their first large animal studies for organ implantation by the end of the year.

“My goal has always been and will always be that we want this to cost the same amount as procurement from a human donor,” says Matheu.

As Matheu looks ahead to the places where more work needs to be done, she points to getting a supply chain to source the right cells for drug therapies and organ development.

So the roadmap for new products begins with the vascular scaffolds, runs through vascularized skin grafts and developing insulin producing cells and vascular shunts for dialysis patients.

“Regenerative medicine has made enormous leaps in recent decades. However, to create complete organs, we need to build higher order structures like the vascular system,� said Dr. Alex Morgan, Principal at Khosla Ventures, in a statement. “Prellis’ optical technology provides the scaffolding necessary to engineer these larger masses of tissues.  With our investment in Prellis, we’re supporting an initiative that will ultimately produce a functioning lobe of the lung, or even a kidney, to be used in addressing an enormous unmet global need.�


Source: TechCrunch

Hackers Can Turn Everyday Speakers Into Acoustic Cyberweapons

A security researcher has demonstrated how to force everyday commercial speakers to emit harmful sounds.
Source: Wired

These are the 10 most disliked videos on YouTube

Ever wondered which videos are the most disliked videos on YouTube? Well, we have the top ten list you’re looking for. Here are the latest videos with the most dislikes currently on YouTube.
Source: Digital trends

Cats movie: Everything we know, from the weird trailer and beyond – CNET

The mutant cat-humans in the preview are hiss-terical, but there’s more to the upcoming movie than Twitter jokes.
Source: CNET

Democratic Presidential nominees are ignoring the issue of our cybersecurity infrastructure

With the long battle for the Democratic nominee for president in 2020 firmly underway, more than 20 political hopefuls are talking about spreading the fruits of a solid economy to millions of middle-class Americans who may have missed the good times, implementing Medicare for all to solve financial healthcare pitfalls, and free college education.

One would-be candidate – Jay Inslee, the governor of the state of Washington – is talking almost exclusively about the need to address climate change far more quickly and far more seriously.
But what has not been discussed by any of them, even briefly, is the stunning existential threat to our critical national security and the entire well-being of the U.S. posed by mounting and painful cyber breaches of infrastructure and other targets. If no would-be candidates can acknowledge the significance and magnitude of the cyber threat – let alone put forward a strategy and plan to defend against the threat – it’s hard to take them seriously as prospective national leaders.
I’m hardly the only one with this view. “When we think about existential threats, government has to understand that electricity doesn’t reside in its own silo and that if something happens to (companies like) us, it would have a potentially cataclysmic impact on finance as well,� utility Southern Company CEO Tom Fanning recently told Fox Business.
Specifically, consider just a few examples of what is going on every day:
 
Election malfeasance. We hear daily outrage about threats to our increasingly digital electoral infrastructure, and yet there is no policy discussion.
 
Rampant theft of intellectual property. The strength of our economy is based on our ability to innovate, as encapsulated in IP. And yet our economic and military rivals are brazenly stealing this IP with impunity. They take our innovation and weaponize it to challenge U.S. industry leadership and compromise our defense military technologies.
 
Targeting of critical infrastructure. When most of our infrastructure was built, it was not with security in mind. Our society is dependent upon our infrastructure. What if our phones didn’t work, we couldn’t bank, electrical and gas service was cut off, our planes couldn’t fly and our ports could not function? Massive financing is required to boost security.
 
Manipulation of privacy by select technology giants. What is, in effect, another sort of breach, is the collection, aggregation and manipulation of our privacy by digital aggregators such as Google and Facebook, which is then further manipulated and stolen by criminals. (Note here: A positive response has been the Federal Trade Commission’s endorsement this month of a $5 billion settlement with Facebook over a long-running probe into its privacy missteps.)
How do we solve these problems? Blatantly dictating solutions would inevitably fail. What we can do successfully is set standards of performance and responsibility, coupled with timelines and severe penalties for failure to perform. There must be accountability –something that sometimes exists in industry (albeit at inadequate levels), but that is wholly missing in government at all levels.
While I care deeply about cybersecurity, I am not naïve about the extreme pressure confronting politicians to score well in polls – a requirement to have a shot at winning their party’s presidential nomination. Arguably, cybersecurity awareness may not fit this bill.
If enhanced cybersecurity is to be injected into the Democratic election agenda, the public must actively promulgate such a step. Supporting an outcry is the irrefutable fact that the signs of risk are flagrant. Earlier this year, Global Risks Report 2019 – published by the World Economic Form – said that the rapid evolution of cyber and technological threats poses one of the most significant dangers to societies around the world.
In the U.S., meanwhile, cybersecurity is now at the forefront of policy discussions and planning for future conflicts. The cyber threat has leveled the playing field in many ways, presenting unique concerns to the U.S. and its allies. Two years ago, the final report of the Department of Defense Science Board Task Force on Cyber Deterrence concluded that cyber capabilities of other nations exceeded U.S. ability to defend systems and said this would remain the case for at least another five to 10 years.
These and other threats manifest themselves through attacks on our digital infrastructure. And as the largest and most digitized economy in the world, we have the most to lose when our infrastructure is comprised. There is no higher priority threat to the U.S. If those who would be our leaders, including Donald Trump, cannot acknowledge such a huge external threat to our security, economy and lifestyle and take steps to resolve it, they have no business vying to become the leader of our nation in 2020.


Source: TechCrunch

DARPA's $10 million voting machine couldn't be hacked at Defcon (for the wrong reasons) – CNET

The voting machine was supposed to be available for hackers to find security flaws. An unexpected bug stopped the experiment from starting until Defcon’s day.
Source: CNET

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