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Archivo del Autor: Belen De Leon

Hospital in China denies links to world’s first gene-edited babies

News of the world’s first ever gene-edited human babies being born in China caused a huge stir on Monday after the MIT Technology Review and the Associated Press brought the project to light. People in and outside China rushed to question the ethical implications of the scientific breakthrough, reportedly the fruit of a Chinese researcher named He Jiankui from a university in Shenzhen.

There’s another twist to the story.

According to the AP, He had sought and received approval from Shenzhen HarMoniCare Women’s and Children’s Hospital to kick off the experiment. The MIT Technology Review’s report also linked to documents stating that He’s research received the green light from HarMoniCare’s medical ethics committee.

When contacted by TechCrunch, however, a HarMoniCare spokesperson said she was not aware of He’s genetic test and that the hospital is probing the validity of the circulated documents. TechCrunch will update when the case makes progress.

“What we can say for sure is that the gene editing process did not take place at our hospital. The babies were not born here either,” the spokesperson said of He’s project.

He, who studied at Rice and Stanford Universities, led a research team at Southern University of Science and Technology which set out to eliminate the gene associated with HIV, smallpox, and cholera by utilizing the CRISPR gene-editing tool, according to the MIT Technology Review. The technology is ethically fraught because changes to the embryo will pass on to future generations. He’s daring initiative is set to cause debate at the upcoming Second International Summit on Human Genome Editing in Hong Kong, which he will attend.

It’s also noteworthy that HarMoniCare belongs to the vast Putian network, a fold of 8,000 private healthcare providers originated from Putian, Fujian province. That’s according to a list compiled by DXY.cn, a Chinese online community for healthcare professionals. Putian hospitals expanded across China quickly over the years with little government oversight until the death of a college student. In 2016, 21-year-old Wei Zexi died of cancer after receiving dubious treatment from a Putian hospital. The incident also provoked a public outcry over China’s largest search engine Baidu, which counted Putian hospitals as a major online advertiser.


Source: TechCrunch

Cyber Monday Special: Buy a pass to Disrupt Berlin 2018 and snag a $200 gift

Disrupt Berlin 2018 kicks off in just three days, the holidays are upon us, and we here at TechCrunch are feelin’ the season. What better way to celebrate both events than to share the spirit of entrepreneurism and gift-giving with a Cyber Monday special.

Today — and today only — when you buy any pass to Disrupt Berlin 2018 (excluding student and government passes) you’ll get to select a gift (up to a $200 USD value not including tax or shipping) from the TechCrunch Holiday Gift Guide. It’s our annual, curated list of all the really good stuff.

Whatever puts you in the holiday mood, we’ve got you covered. STEM gifts for the kids, podcast tools, something for the frequent flyer in your life or maybe a little tchotchke just for you (we won’t tell).

Gifts are great — especially the $200 variety. But the coolest gift you can give yourself this year is a ticket to Disrupt Berlin 2018. Talk about a gift that keeps on giving.

It’s the gift of opportunity — network and connect with founders, investors, developers and more — every stripe of tech enthusiast imaginable. Find future partners and customers. Explore hundreds of early-stage companies exhibiting in Startup Alley, hear from top tech and investment leaders, enjoy the thrill ride that is Startup Battlefield.

No matter where you roam or who you want to meet at Disrupt Berlin, we’ve made networking easier than ever by making our free business match-matching service, CrunchMatch, available to all attendees.

Go buy your pass to Disrupt Berlin 2018, and then we’ll be in touch the week of 3 December to coordinate your something sweet from our awesome gift guide. We can’t wait to see you in Berlin!


Source: TechCrunch

Cyber Monday 2018: Xbox One S, Xbox One X deals continue starting at $199 – CNET

Looking for the best deals on Xbox One S and Xbox One X? The Cyber Monday sales are here.
Source: CNET

Cyber Monday 2018 Nintendo Switch deals: New Nintendo Switch deals incoming – CNET

You might be able to score the console alone for just $250. And here’s where you can get that Mario Kart 8 Deluxe bundle right now. Also — Labo is cheap!
Source: CNET

Cyber Monday 2018: $199 PS4 Spider-Man sold out, but $200 PS4 with Red Dead Redemption 2 is live! – CNET

The Spider-Man bundle appears sold out nearly everywhere — but stepping up to the PS4 Pro can get you a free copy of Red Dead Redemption 2. Dozens of other PS4 deals are available today, too.
Source: CNET

Watch Live as NASA's InSight Lander Descends to Mars

These livestreams will let you follow along as the InSight spacecraft lowers itself to the surface of Mars.
Source: Wired

USPS fixes online flaw that exposed the data of 60 million customers

The United States Postal Service has patched an online security flaw that allowed anyone with an account at usps.com to view the account details of any of the 60 million people signed up to the service.

The post USPS fixes online flaw that exposed the data of 60 million customers appeared first on Digital Trends.


Source: Digital trends

CRISPR scientist in China claims his team’s research has resulted in the world’s first gene-edited babies

In what would represent a dramatic and ethically fraught escalation of CRISPR research, a Chinese scientist from a university in Shenzhen claims he has succeeded in helping create the world’s first genetically-edited babies. Dr. Jiankui He told the Associated Press that twin girls were born earlier this month after he edited their embryos using CRISPR technology to remove the CCR5 gene, which plays a critical role in enabling many forms of the HIV virus to infect cells.

The AP’s interview was published after a report by the MIT Technology Review earlier today that He’s team at the Southern University of Science and Technology wants to use CRISPR technology to edit out the CCR5 gene and create children with resistance to HIV.

It is important to note that there is still no independent confirmation of He’s research and that it has not been published in a peer-reviewed journal, but his claims are certain to cause a huge stir at the Second International Summit on Human Genome Editing, set to begin in Hong Kong on Tuesday. According to the Technology Review, the summit’s organizers were apparently not notified of He’s plans for the study, though the AP says He informed them today.

During his interview with the AP, He, who studied at Rice and Stanford before returning to China, said he felt “a strong responsibility that it’s not just to make a first, but also make it an example” and that “society will decide what to do next.”

According to documents linked by the Technology Review, the study was approved by the Medical Ethics Committee of Shenzhen HOME Women’s and Children’s Hospital. The summary on the Chinese Clinical Trial Registry also said the study’s execution time is between March 7, 2017 to March 7, 2019, and that it sought married couples living in China who met its health and age requirements and are willing to undergo IVF therapy. The research team wrote that their goal is to “obtain healthy children to avoid HIV providing new insights for the future elimination of major genetic diseases in early human embryos.”

A table attached to the trial’s listing on the Chinese Clinical Trial Registry said genetic tests have already been carried out on fetuses of 12, 19, and 24 weeks of gestational age, though it is unclear if those pregnancies included the one that resulted in the birth of the twin girls, whose parents wish to remain anonymous.

“I believe this is going to help the families and their children,” He told the AP, adding that if the study causes harm, “I would feel the same pain as they do and it’s going to be my own responsibility.”

Chinese scientists at Sun Yat-sen University in Guangzhou first edited the genes of a human embryo using CRISPR technology (the acronym stands for Clustered Regularly Interspaced Short Palindromic Repeats), which enables the removal of specific genes by acting as a very precise pair of “genetic scissors,” in 2015. Though other scientists, including in the United States, have conducted similar research since then, the Southern University of Science and Technology’s study is considered especially radical because of the ethical implications of CRISPR, which many scientists fear may be used to perpetuate eugenics or create “designer babies” if carried out on embryos meant to be carried to term.

As in the United States and many European countries, using a genetically-engineered embryo in a pregnancy is already prohibited in China, though the Technology Review points out that this guideline, which was issued to IVF clinics in 2003, may not carry the weight of the law.

In 2015, shortly after the Sun Yat-sen University experiment (which was conducted on embryos that were unviable because of chromosomal effects) became known, a meeting called by several groups, including the National Academy of Sciences of the United States, the Institute of Medicine, the Chinese Academy of Sciences and the Royal Society of London, called for a moratorium on making inheritable changes to the human genome.

In addition to ethical concerns, Fyodor Urnov, a gene-editing scientist and associate director of the Altius Institute for Biomedical Sciences, a nonprofit in Seattle, told the Technology Review that He’s study is cause for “regret and concern” because it may also overshadow progress in gene-editing research currently being carried out on adults with HIV.

TechCrunch has contacted He for comment at his university email.


Source: TechCrunch

Watch NASA's InSight land in the middle of Times Square, just like the movies – CNET

Stop in the middle of Times Square, grab a stranger’s hand and stare in wonderment as NASA survives the “seven minutes of terror” to land InSight on Mars.
Source: CNET

Cyber Monday 2018 Target deals: $25 Google Home Mini, $70 Bose SoundLink Micro, Fitbits, Roku and more – CNET

The latest deals and discounts include savings on Google, Amazon and Bose products.
Source: CNET

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